222-Trifluoroethanol CAS No 75-89-8

2,2,2-Trifluoroethanol – CAS 75-89-8

2,2,2-Trifluoroethanol (CAS 75-89-8) is a colorless liquid with a strong odor. Its basic structure consists of a central carbon atom bonded to three fluorine atoms and one hydroxyl group. This compound is highly soluble in water, alcohol, and ether. It has a boiling point of 74.4°C and a melting point of -38.3°C. 2,2,2-Trifluoroethanol is flammable and can form explosive mixtures with air. It reacts violently with strong oxidizing agents and can release toxic fumes when heated.

Description

222-Trifluoroethanol CAS No 75-89-8

222-Trifluoroethanol CAS No 75-89-8 for sale online at research chemicals lab. Our 2,2,2-Trifluoroethanol is the organic compound with the formula CF3CH2OH. Also known as TFE or trifluoroethyl alcohol, this colourless, water-miscible liquid has a smell reminiscent of ethanol. Due to the electronegativity of the trifluoromethyl group, this alcohol exhibits a stronger acidic character compared to ethanol. Thus, TFE forms stable complexes also with heterocycles (e.g. THF or pyridine) through hydrogen bonding.

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 Specification of our 2,2,2 Trifluoroethanol CAS No 75-89-8

Item Result
Appearance Colorless clear liquid
Assay ≥99.8
Water content ≤0.06
Fluoride, F % ≤0.0015
Chloride, CL– % ≤0.001
PH (10% aqueous solution) 5-7

2,2,2-Trifluoroethanol

2,2,2-trifluoroethanol or trifluoroethanol is called TFEA or TEF. It is important intermediate of the fluorine-containing aliphatic, it is colorless, it is miscible liquids with water, it has similar odor with ethanol. Due to the strong electron-withdrawing effect of trifluoromethyl, acid of trifluoromethyl is stronger than ethanol. It can generate hydrogen-bonded stable complex (such as: tetrahydrofuran, pyridine) with heterocyclic compound.

Due to this unique physical and chemical properties and special molecular structure, it has different performance with other alcohols. Also, it can participate in a variety of organic reactions. It can be oxidized to acetaldehyde trifluoromethyl or trifluoroacetic acid. It can also provide trifluoromethyl, it can participate in the Still-Gennari improvements of Horner-Wadsworth-Emmons reaction.

222-Trifluoroethanol CAS No 75-89-8

It has wide range of uses in medicine, pesticides, dyes, energy, and other aspects of organic synthesis.The main use of trifluoroethanol is as anesthetic, at the earliest, fluorine acetylene ether which synthesized by trifluoroethanol and acetylene takes place of bigger side effects of bromine-fluoro alkanes as anesthetic.  In addition, the trichloroethanol is used as raw material to develop non-flammable. Thus, low toxicity isoflurane alkanes and high performance of the new anesthetic of chlorofluoroalkane.

Trifluoroethanol can be introduced into drug structure as trifluoromethyl of functional group. It can generate significant physiological activity, increase fat-soluble of molecules, improve efficacy or reduce side effects of the organism. Its synthetic drugs have central nervous system stimulants fluticasone Seoul. Substituted pyridines stomach cytoplasmic proton pump inhibitor Lansoprazole and Pariprazole. Antiarrhythmic drugs flecainide with amines and analgesic drugs benzodiazepines and dysuria treatment KMD-3212 and so on.

222-Trifluoroethanol 75-89-8 Usage:

As a solvent, can be used as trifluoroethyl and trifluoroethoxide Ionomycin, also used as medicine, pesticide intermediates.

222-Trifluoroethanol Packaging and Shipping:

250KG/drum or as per buyer requirements

222-Trifluoroethanol  Storage:

Storage in ventilated low temperature dry warehouse; Keep container closed and separately from open flame and heat source, Store separately from oxidizer.

Fine chemicals, mainly includes flame retardant, pharmaceutical raw materials & intermediates. Our products are exported to many countries and areas such as Europe, North America, South America, Southeast Asia, etc.

 

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