Tris(2-carboxyethyl) phosphine hydrochloride

Tris(2-carboxyethyl)phosphine hydrochloride CAS No.: 51805-45-9

Chemical Name: Tris(2-carboxyethyl) phosphine hydrochloride

CAS No.: 51805-45-9

Assay: ≥99.50%

Appearance: White powder

Description

Tris(2-carboxyethyl) phosphine hydrochloride CAS No: 51805-45-9

Tris(2-carboxyethyl) phosphine hydrochloride for sale online at Research Chemicals Lab.

TCEP, Hydrochloride is a water soluble, non-thiol, strong reducing agent shown to cleave disulfide bonds. Reports indicate that TCEP, Hydrochloride can rapidly reduce stable alkyl disulfides, including DTT. TCEP, Hydrochloride has been observed to reduce DHA in a solution of EDTA and metaphosphoric acid.
Also, TCEP, Hydrochloride is also used to conduct proteolysis and Hydrogen/Deuterium exchange. Binding studies demonstrate that TCEP, Hydrochloride does not bind Hg2+, and its binding efficacy to NF-κB-DNA has been tested in vitro. TCEP, Hydrochloride is also known as tris(2-Carboxyethyl) phosphine HCl, 3,3,3-Phosphinidynetrispropanoic Acid Hydrochloride, 3-bis(3-oxido-3-oxopropyl) phosphanylpropanoate, and propanoic acid, 3, 3′, 3′ ′ -phosphinidynetris-, hydrochloride.

Tris(2-carboxyethyl) phosphine hydrochloride Specification:

Item Testing results
Appearance White powder
Purity ≥99.5%
Melting point 170.0-180.0℃

 

Tris(2-carboxyethyl) CAS No 51805-45-9 Usage/Application:

It can be used as water-soluble reagent for selective reduction of disulfide. It is more stable than DTT in mass spectrometry applications. Also, it can also be used for selective reduction of disulfide in water.

  • Tris(2-carboxyethyl) phosphine hydrochloride (TCEP. HCl) can be used:
    As a reducing agent for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It can also be used in azide-alkyne cycloaddition reaction in the presence of a copper catalyst.
  • To reduce disulfide bonds in various proteins.
    As a reagent for the selective reduction of disulfides in water.
  • To remove ruthenium-derived metathesis catalysts via aqueous washing of a crude reaction mixture when it is basified.
  • As a reducing agent for the reduction of various alkyl disulfides such as trans-4,5-dihydroxy-1,2-dithiane.
    Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.

CAS No 51805-45-9 Packaging and Shipping:

25KG/drum or as per buyer requirement.

CAS No 51805-45-9 Storage:

Store in a cool, dry and ventilated warehouse; Keep the container airtight.

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